Management of infections caused by carbapenemase-producing Enterobacterales in France: a real-world study.

ABSTRACT:

Background

Carbapenemase-producing Enterobacterales (CPE) are a significant public health concern, with limited treatment options and high mortality rates. The epidemiology and management of CPE infections in France remain insufficiently documented.

Objectives

To provide a multicentre snapshot of the management of CPE infections in France, assess current clinical practices and evaluate their alignment with international guidelines.

Methods

We conducted a multicenter, observational, cross-sectional study across 31 French hospitals between September 2021 and March 2023. Adult patients with confirmed CPE infections were included. Clinical and microbiological data were collected retrospectively. Treatment regimens were analysed, and therapeutic appropriateness was assesse

SUBMITTER: Pilmis B 

PROVIDER: S-EPMC12784193 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature