Multiple brain activation patterns underlying successful visual short-term memory across the adult lifespan.

ABSTRACT: Cognitive task performance can be supported through multiple brain activation patterns, a concept referred to as brain degeneracy. We used a novel approach to consider brain degeneracy during a visual short-term memory task (VSTM) across the adult lifespan in the cross-sectional Cam-CAN study (n = 113, 23-87 years old). Our main goal was to identify subgroups of participants whose VSTM performance was characterized by distinct brain activation patterns. First, we identified seven brain modules that responded similarly to the VSTM task across participants, and resembled previously identified functional networks. Subsequently, latent profile analysis revealed four distinct subgroups of participants. Each subgroup was characterized by different recruitment patterns of these modules, predomina

SUBMITTER: Jansen MG 

PROVIDER: S-EPMC12784220 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature