Safety and Feasibility of Extended Platelet-Rich Fibrin as a Solo Barrier Membrane for Ridge Preservation: A Case Series.

ABSTRACT:

Introduction

Platelet-rich fibrin (PRF) has been commonly utilized for ridge preservation techniques either to introduce supraphysiological concentrations of autologous growth factors to the defect area (typically when mixed within a bone graft) or utilized alone as a solo "barrier" membrane. Noteworthy, however, one of the commonly reported drawbacks of PRF is its relatively short resorption period characterized by lasting roughly 2 weeks. This may therefore be insufficient for complete soft tissue closure and/or preventing soft tissue cells from infiltrating into the bony compartment. Recently, it was discovered that by heating plasma and denaturing albumin using the Bio-Heat technology, the resorption properties of PRF could be extended from a standard 2-3 week period toward 4-6

SUBMITTER: Estrin NE 

PROVIDER: S-EPMC12784283 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature