Asynchronous Stepped Fourier Transform Ion Mobility Spectrometry.

ABSTRACT: Fourier Transform is a low-cost method for improving duty cycle, resolving power, and signal-to-noise ratio in the Ion Mobility Spectrometry (IMS) experiment in a 2-gate IMS cell. By simultaneously pulsing both gates through a frequency sweep, the resulting data may be deconvoluted into a time-based mobility spectrum through a Fast Fourier Transform (FT). However, inconsistencies common in low-cost function generators result in spectral artifacts. In this work, an asynchronous stepped frequency FTIMS method is demonstrated, which uses a simple, software timed pulse generator compatible with any modern Analog-Digital Converter (ADC) system. By unlinking the frequency initiation and data collection using a long rise-time amplifier circuit, a stand-alone FTIMS with Faraday Plate detection was

SUBMITTER: Edstrom E 

PROVIDER: S-EPMC12784390 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature