Inflammation Indices as Predictive Markers of Muscle-Invasive Bladder Cancer.

ABSTRACT:

Introduction

Prompt diagnosis and differentiation between non-muscle-invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC) are essential in the treatment of bladder cancer. Inflammation-based biomarkers have recently emerged as potential tools for improving cancer diagnostics and prognostication. This study aims to evaluate the potential value of the Systemic Inflammation Index (SII), Systemic Inflammation Response Index (SIRI), Pan-immune Inflammation Value (PIV), and Platelet-to-Lymphocyte Ratio (PLR) as predictors of muscle-invasive disease.

Materials and methods

Analyzed data included 310 bladder tumors. The SII, SIRI, PIV, and PLR were calculated from pre-TURBT complete blood-count results. Differences in inflammatory markers between pathological sta

SUBMITTER: Jaromin M 

PROVIDER: S-EPMC12784776 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature