Molecular Characteristics and Pathogenicity Analysis of Bovine Viral Diarrhea Virus Strain Isolated from Persistently Infected Cattle.

ABSTRACT: Bovine viral diarrhea virus (BVDV) primarily causes bovine viral diarrhea/mucosal disease, an infectious disease having a significant economic impact on the cattle-farming industry globally. Comprehensive monitoring and in-depth studies of the pathological characteristics of viruses are crucial in formulating effective prevention and control strategies. The isolation, identification, molecular characterization, and pathogenicity analysis of a BVDV strain isolated from persistently infected cattle ear tissue samples are reported in this study. This newly isolated strain is a noncytopathogenic BVDV, which we named HB2411. Homology between the HB2411 and U63479 strains was determined to be 96.7%, and the phylogenetic tree indicated that HB2411 belongs to the BVDV-1b subtype. Gen

SUBMITTER: Zhong J 

PROVIDER: S-EPMC12784899 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature