Association Between Dietary Magnesium Intake and Low Muscle Mass: The Mediating Role of Inflammatory Indicators.

ABSTRACT: Background: Magnesium is essential for mitochondrial function and muscle regeneration, potentially protecting against low muscle mass (LMM). We examined the association of dietary magnesium intake with LMM risk and skeletal muscle index (SMI), and whether inflammatory indicators mediate this relationship. Methods: A total of 5793 participants aged 20-59 years were included in this study from the National Health and Nutrition Examination Survey (NHANES) conducted from 2011 to 2018. To investigate the association of dietary magnesium intake with LMM and SMI, we applied weighted logistic regression model, linear regression model, restricted cubic spline analysis, subgroup analysis and sensitivity analysis. Inflammatory indicators were assessed using mediation analysis, including

SUBMITTER: Zhu Z 

PROVIDER: S-EPMC12785460 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature