Valorization of Isabella Grape (<i>Vitis labrusca</i> L.) Pomace Through the Recovery of Nutraceuticals by Sequential Green Extraction Technologies.

ABSTRACT: Isabella grape pomace (IGP) the primary by-product of Colombia's winemaking industry, represents a promising source of nutraceuticals with potential uses in the food industry. This study developed a sequential green extraction process to recover nutraceutical from IGP. The approach integrated supercritical fluid extraction with CO₂ (SFE-CO₂) to obtain lipophilic compounds, followed by SFE with ethanol/water as co-solvent (SFE-CO₂/EtOH:H₂O) for medium-polarity phenolics, and pressurized liquid extraction (PLE) with EtOH:H₂O to recover the polar phenolic-rich fraction. The extraction parameters were optimized using response surface methodology, and optimal conditions were identified: SFE-CO₂ at 31.7 MPa/58.9 °C yielded 6.95% e

SUBMITTER: Sanchez JS 

PROVIDER: S-EPMC12785773 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature