Anticancer Mechanisms of Bioactive Compounds from Sweet Potato (<i>Ipomoea batatas</i> L.) Leaves: A Systematic Review.

ABSTRACT: Sweet potato leaves (SPL) are increasingly recognized as a significant source of nutritionally and pharmacologically important bioactive compounds. This systematic review critically synthesizes current in vitro, in vivo, and preclinical data to evaluate the cancer preventive properties of SPL, with emphasis on their phytochemical composition, molecular mechanisms, and therapeutic relevance. A comprehensive literature search across major scientific databases (2015-2025), guided by PRISMA methodology, initially identified 29,416 records. After applying pre-specified inclusion and exclusion criteria and screening titles, abstracts, and full-texts, 38 eligible studies were included. The compiled evidence demonstrates that SPL contains high concentrations of phenolic acids, flavonoids, peptides

SUBMITTER: Chowdhury SS 

PROVIDER: S-EPMC12785916 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature