Soft Micromanipulation Robot for Real-Time Adaptive Multimodal Operation.

ABSTRACT: Micromanipulation robots hold immense promise for biomedical applications, yet they remain fundamentally limited by three persistent challenges: cross-scale target heterogeneity, spatially constrained workspaces, and integrated multimodal operation requirements. Here, a soft micromanipulation robot (SMR) capable of omnidirectional, micrometer-precision manipulation via a hollow multi-notch agonist-antagonist mechanism is presented. Combining ± 180° bending and 360° rotation for full-angle operation, this bio-inspired design achieves 14 µm positioning accuracy, enabling reliable handling of single-cell-sized objects. The SMR adapts in situ to sensitive biosamples and limited workspaces, supporting diverse manipulation modes including aspiration, transfer, programmable assembly, targeted mic

SUBMITTER: Li Z 

PROVIDER: S-EPMC12786275 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature