Synergistic Anti-Cancer Therapy Through Ultrasound-Induced Piezocatalytic Therapy and Tumor Treatment Fields.

ABSTRACT: The integration of therapeutic modalities to enhance cancer treatment efficacy and improve patient outcomes offers remarkable benefits over monotherapies and has attracted considerable attention. Herein, a synergistic anti-cancer therapy leveraging the benefits of physical tumor treating fields (TTFs) and dynamic piezocatalytic therapy (PCT) is presented, aiming to offer an optimized scheme while minimizing systemic side effects. First, a wearable ultrasound-induced wireless energy harvester based on biocompatible lead-free potassium sodium niobate-based piezocomposites is developed to enable efficient acoustic-to-electric conversion. The flexible printed circuit board architecture with two pairs of half-ring electrodes not only generates wide-anging alternating electric fields but also fa

SUBMITTER: Jin J 

PROVIDER: S-EPMC12786362 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature