Design, Sustainable Processing and Nanoliposome Encapsulation of Red Grape Pomace Rich in Polyphenolic Compounds with Antioxidant Activity.

ABSTRACT: In this study, we aimed to investigate the potential of utilizing red grape pomace as a source of polyphenolic compounds in the growing, fragmented winemaking sector in Poland. For polyphenol extraction, we compared two methods: conventional extraction using water and alcohol solutions, and the supercritical CO₂ technique with ethanol as a cosolvent. The conventional method yielded at least 30% more polyphenols compared to the advanced SC-CO₂ technique. Experimentally chosen conditions, including a solvent composition of ethanol-water (1:1; v/v) containing 3% HCl, a liquid-to-solid ratio of 25:1 mL/g, and 2 min of ultrasound pretreatment and conventional extraction at a temperature of 30 °C over 4.5 h, enabled an extraction efficiency of 101 mg of total

SUBMITTER: Haldys K 

PROVIDER: S-EPMC12786665 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature