The Impact of Probiotics on Clinical Outcomes in Diverticular Disease: A Systematic Review and Meta-Analysis.

ABSTRACT: Background/Objectives: Diverticular disease (DD) affects a significant portion of the aging population and is increasingly linked to gut microbiota alterations. Probiotics have emerged as a potential adjunct therapy, particularly in managing symptoms and inflammation. The evidence for the recommended use of probiotics in clinical practice for management of diverticular disease is still a matter of controversy. Methods: A comprehensive literature search was conducted across five major databases up to October 2024. Eligible studies included randomized controlled trials (RCTs) and observational studies assessing probiotic use in adult patients with diverticular disease. Results: Thirteen studies met the eligibility criteria. Probiotic therapy was associated with improveme

SUBMITTER: Alnajjar JS 

PROVIDER: S-EPMC12786911 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature