Reconstructive Strategies After Mastectomy: Comparative Outcomes, PMRT Effects, and Emerging Innovations.

ABSTRACT: Background: Advances in breast reconstruction have transformed the recovery pathway for women undergoing mastectomy. What was once viewed mainly as a cosmetic option is now recognized as part of modern oncologic care, restoring not only body image but also confidence and quality of life. Yet, surgeons still face the same central dilemma: choosing between implant-based (IBR) and autologous reconstruction (ABR), particularly when postmastectomy radiotherapy (PMRT) is planned. Methods: We reviewed major studies published between 2014 and 2024, combining evidence from observational cohorts and recent meta-analyses that together report on more than 60,000 reconstructed breasts. Outcomes of interest included surgical complications, reconstructive failure, BREAST-Q patient-reported

SUBMITTER: Stana M 

PROVIDER: S-EPMC12786912 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature