<i>Ginkgo biloba</i> Extract EGb 761^® in Patients with Chronic Tinnitus: Treatment Effects and Effect Modifiers.

ABSTRACT: Background/Objectives: An exploratory study was conducted to investigate the effect of Ginkgo biloba extract EGb 761^® in the management of chronic tinnitus, and whether comorbidities have an impact on the treatment outcome. Methods: The exploratory, uncontrolled, open-label study enrolled 170 patients (Full Analysis Set) with chronic tinnitus who took 120 mg EGb 761^® twice daily for 24 weeks. Outcomes were assessed using the Tinnitus Questionnaire, Tinnitus Handicap Inventory, and 11-Point Box Scales for loudness and annoyance. Comorbidities were recorded with audiometry, the Hospital Anxiety and Depression Scale, and the Perceived Stress Questionnaire. The effectiveness was further examined in responder analyses (at least 30% score reduction in 3

SUBMITTER: Lisowska G 

PROVIDER: S-EPMC12787070 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature