Site-Specific Recruitment, Localization of Ionized Monomer to Macromolecular Crowded Droplet Compartments Can Lead to Catalytic Coacervates for Photo-RAFT in Dilution.

ABSTRACT: Catalytic coacervates, or droplet reactors, represent a forefront research area in chemistry and materials science. Despite advancements in this field, challenges persist in achieving liquid-liquid phase separation (LLPS) droplet compartmentalization and site-specific reactant recruitment/localization for reaction catalysis, similar to those within biological systems. Herein, we describe the catalytic coacervates for aqueous photo-RAFT in dilution, focusing on the site-specific recruitment/localization of ionized monomer with the aid of macromolecular crowding and confinement. Cooperative hydrogen-bonded interpolymer complexation (IPC) of imidazolium-copolymers initiates the ion-cluster formation. Further hierarchical inter-cluster complexation (ICC) leads to the LLPS droplet compar

SUBMITTER: Niu W 

PROVIDER: S-EPMC12787518 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature