Whole-brain meso-vein imaging in living humans using fast 7-T MRI.

ABSTRACT: Noninvasive measurement of the human brain's angioarchitecture is essential for understanding functional neuroimaging signals, diagnosing cerebrovascular diseases, and tracking neurodegeneration. Ultrahigh-field MRI now enables mesoscopic (<0.5 millimeters) imaging, revealing vascular details previously inaccessible in vivo. Yet current approaches face two barriers: Scan times often exceed 40 minutes, and the conventional visualization methods remain limited for navigating the vasculature. Here, we present a fast whole-brain MRI protocol that resolves the venous network at 0.35 millimeters in under 7 minutes. We also introduce processing and visualization techniques that distinguish vessel types and more intuitively navigate the vasculature. These advances allow in vivo reproduction of the

SUBMITTER: Gulban OF 

PROVIDER: S-EPMC12787541 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature