Influence of Diet on the Bioaccessibility of Zn from Dietary Supplements: Findings from an In Vitro Digestion Model and Analytical Determinations.

ABSTRACT:

Background

Zn is an essential mineral nutrient for human health. Its deficiency may result not only from insufficient intake but also from impaired absorption. Dietary components released from the food matrix during digestion can interact in ways that either enhance or inhibit mineral bioavailability.

Objectives

The primary aim of this study was to evaluate the bioaccessibility of Zn from dietary supplements, particularly in the context of diet type, chemical form, and pharmaceutical formulation effects.

Methods

The experiment was conducted using an in vitro gastrointestinal digestion model with cellulose dialysis membranes. Zn content after digestion was determined using flame atomic absorption spectrometry (F-AAS). The method employed had been previously developed a

SUBMITTER: Tokarczyk J 

PROVIDER: S-EPMC12788010 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature