A Five-Electrode Contactless Conductivity Detector Based on a Sandwiched Microfluidic Chip for Miniaturized Ion Chromatography.

ABSTRACT: This study aims to develop a chip-based five-electrode contactless conductivity detector for miniaturized ion chromatography (IC) systems. The detector comprises a detection chip (50 mm × 25 mm × 6 mm) and a detection circuit. The detection chip consists of a top layer, an insulating film, and a bottom layer wherein a planar five-electrode printed circuit board (PCB) is embedded. Among the five electrodes, one shielding electrode is designed to suppress the leakage current in the flow channel; consequently, the potential at the solution outlet is raised, further enhancing detection sensitivity. Furthermore, integrating the electrodes into a PCB module can reduce the difficulty of electrode fabrication and extend the lifespan of the electrodes. The detector was applied to a commercial IC sy

SUBMITTER: Chen K 

PROVIDER: S-EPMC12788068 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature