Purified Anthocyanins Indicated No Significant Effect on Arterial Stiffness, Four-Limb Blood Pressures and Cardiovascular Risk-A 12-Week Dose-Response Trial in Chinese Middle-Aged and Elderly Adults with Hyperglycemia.

ABSTRACT: Background: Diabetes is associated with sub-optimal vascular function. Current evidence suggested purified anthocyanins (ACNs) could improve cardio-metabolic health, but the dose-response effects on arterial stiffness have not been verified. Objectives: To assess the dose-responsiveness of purified ACNs on vascular stiffness and cardiovascular risk among Chinese middle-aged and elderly patients with either prediabetes or early diabetes. Methods: This was a secondary analysis based on a 12-week double-blind, randomized and placebo-controlled trial. Eligible participants were randomly assigned to placebo, 160, 320 and 640 mg/d ACNs groups (n = 46/group). Information on dietary intakes and lifestyle habits and blood samples were collected at baseline and at week 12

SUBMITTER: Liu Z 

PROVIDER: S-EPMC12788160 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature