TEPEAK: A novel method for identifying and characterizing polymorphic transposable elements in non-model species populations.

ABSTRACT: Transposable elements (TEs) replicate within genomes and are an active source of genetic variability in many species. Their role in immunity and domestication underscores their biological significance. However, analyzing TEs, especially within lesser-studied and wild populations, poses considerable challenges. To address this, we introduce TEPEAK, a simple and efficient approach to identify and characterize TEs in populations without any prior sequence or loci information. In addition to processing user-submitted genomes, TEPEAK integrates with the National Center for Biotechnology Information (NCBI) Sequence Read Archive (SRA) to increase cohort sizes or incorporate proximate species. Our application of TEPEAK to 257 horse genomes spanning 11 groups reaffirmed established genetic historie

SUBMITTER: Burke D 

PROVIDER: S-EPMC12788660 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature