Global burden and projections of cervical cancer attributable to unsafe sex and smoking, 1990-2034.

ABSTRACT:

Objectives

To analyze global trends and attributable risks (smoking and unsafe sex) in disease burden of cervical cancer from 1990 to 2034, considering different sociodemographic index (SDI) levels.

Methods

Data from the Global Burden of Disease 2019 study was utilized. Quantile regression, restricted cubic spline, and Nordpred models were applied to analyze the relationship between cervical cancer age-standardized mortality rates (ASMRs), age-standardized Disability-Adjusted Life Years rates (ASDRs) and SDI, and predicted future trends.

Results

From 1990 to 2019, global cervical cancer ASMR declined but the total deaths increased. Unsafe sex accounted for the highest disease burden, particularly in low-SDI regions, followed by smoking. By 2034, ASMR attributed to uns

SUBMITTER: Hu J 

PROVIDER: S-EPMC12788690 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature