Transcription Factor PFB1 Is Required for the Botrytis cinerea Effector BcSCR1-Mediated Pathogenesis.

ABSTRACT: Botrytis cinerea is a necrotrophic fungus that infects more than 200 plant species, causing significant economic losses worldwide. Due to its diverse pathogenicity, extensive efforts have been made to unravel its pathogenic mechanisms. However, the function of the effectors underlying B. cinerea virulence remains largely unknown. In this study, we identified an effector BcSCR1 (B. cinerea small cysteine-rich protein 1) and found that it interacts with the transcription factor PFB1 (Pericycle Factor Type-B1) in Arabidopsis thaliana. Ectopic expression of BcSCR1 in plants resulted in decreased resistance to B. cinerea infection, while disruption of BcSCR1 in B. cinerea significantly decreased its aggressiveness toward host plants. In addition, the mutation of PFB1 in Arabidopsis increased re

SUBMITTER: Li X 

PROVIDER: S-EPMC12789189 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature