A Qualitative Study on Patient Experience with Signs, Symptoms, and Daily Impacts of Immune Thrombocytopenia.

ABSTRACT:

Background

Primary immune thrombocytopenia (ITP) adversely impacts a patient's health-related quality of life (HRQoL).

Objective

This study explored patients' experiences with signs, symptoms, and impacts of ITP and updated the conceptual disease model for HRQoL in patients with ITP.

Methods

Adult patients with ITP were included in the study. Patients with any comorbidity where fatigue was a key symptom (e.g., anemia) were excluded. A concept elicitation interview assessed signs, symptoms, and impacts from the patients' perspective, and cognitive debriefing assessed the validity of the selected patient-reported outcome instruments (ITP-Patient Assessment Questionnaire, Patient Global Impression of Severity of Fatigue, Patient Global Impression on Severity, and Patient

SUBMITTER: Ghanima W 

PROVIDER: S-EPMC12789228 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature