Utility-weighted modified rankin scale scores in patients with ischemic stroke: a multicenter observational study.

ABSTRACT:

Purpose

This study assessed patient-reported health-related quality of life (QOL) in a real-world cohort of patients with ischemic stroke and estimated utility-weighted modified Rankin Scale (UW-mRS) scores.

Methods

We included 1452 patients with ischemic stroke (median age: 75 [67-83] years; 41.0% female) from a multicenter hospital-based stroke registry in Japan. QOL was evaluated using the EQ-5D-5L with Japanese-specific utility values. Both EQ-5D utility values and mRS scores were assessed after completion of acute treatment. UW-mRS scores were estimated using ordinary least squares (OLS) and Tobit regression models.

Results

The mean (SD) EQ-5D utility value was 0.68 (0.27). Higher mRS scores were associated with greater severity and frequency of problems across E

SUBMITTER: Irie F 

PROVIDER: S-EPMC12789241 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature