Transcatheter Tricuspid Valve Replacement in the Presence of Pacemaker Lead-Related Tricuspid Regurgitation and Complex Anatomy.

ABSTRACT:

Background

Cardiac implantable electronic device (CIED)-related tricuspid regurgitation (TR) is increasingly recognized, necessitating heart team assessment. Transcatheter tricuspid valve replacement (TTVR) is emerging as an option for inoperable patients with TR, requiring decisions on right ventricular lead management.

Case summary

A 76-year-old woman developed moderate to severe TR after pacemaker implantation, which was exacerbated by a second RV lead 8 years later, leading to torrential TR and recurrent heart failure hospitalizations. TR persisted despite lead extraction, and multimodality imaging revealed complex valve anatomy. TTVR was performed, yielding excellent echocardiographic results and improved quality of life.

Discussion

CIED and TR can coexist, obscuring the distinction between lead-related and lead-associated TR because of right ventricular remodeling. The heart team should determine lead management during transcatheter procedures. TTVR is a valuable option for massive gaps, severe tethering, or complex anatomy.

Take-home message

Collaborative management with electrophysiology as part of the extended heart team is key in CIED-related TR cases.

SUBMITTER: Patrascu A 

PROVIDER: S-EPMC12789727 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature