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First-in-Human Experience With Septal Occluder for Dehiscence of Anterior Mitral Valve Leaflet Patch: From Surgical to Percutaneous Closure.


ABSTRACT:

Background

Mitral regurgitation secondary to infective endocarditis is often due to structural damage to the leaflets or apparatus, and the condition warrants surgical treatment. If surgery fails, percutaneous repair may be a viable option.

Case summary

We describe a case of anterior mitral valve leaflet perforation after infective endocarditis, initially treated by surgical patch repair, with subsequent dehiscence leading to recurrence of severe mitral regurgitation. After percutaneous closure with a septal occluder device, regurgitation was abolished.

Discussion

To our knowledge, this is the first case to demonstrate use of the Gore Cardioform septal occluder to treat postsurgical dehiscence of anterior mitral valve leaflet patch. Device selection needs to be decide

SUBMITTER: Patrascu A 

PROVIDER: S-EPMC12789739 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature