OmNI: a modular open-source framework for interactive multi-omics data integration and visualization.

ABSTRACT: Omics Notebook Interactive (OmNI) is an R-based, open-source, and modular framework engineered for streamlined multi-omics data integration and analysis across diverse data types, incorporating interactive visualizations at each processing step. OmNI performs differential expression analysis utilizing customizable linear models, accommodating various covariates and complex experimental designs. For cross-omic layer integration, OmNI employs a modified S-score statistic, ensuring sensitive detection of differential features. The framework also integrates network and metabolomics data, offering detailed insights into regulatory mechanisms through comprehensive enrichment analysis using multiple pathway databases. Outputs include interactive HTML reports, CSV/TSV files, and Cytoscape-c

SUBMITTER: Potter G 

PROVIDER: S-EPMC12789801 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature