Very high CO₂ concentrations inhibit photosynthesis and trigger transcriptomic stress responses in cyanobacteria.

ABSTRACT: CO[Formula: see text] concentrations above air level (0.04%) are beneficial for the growth of cyanobacteria. However, very high CO[Formula: see text] levels inhibit growth, limiting the usability of cyanobacteria for carbon capture and biotechnological applications. The transcriptomic changes in the cyanobacterium Synechococcus sp. PCC 7002 were investigated at varying growth rates governed by different gas-phase CO[Formula: see text] concentrations, ranging from limiting (0.04%) to optimal (4% and 8%) to inhibitory high (30%). Compared to optimal CO[Formula: see text] concentrations, large differences in the transcriptome were observed in limiting and inhibiting CO[Formula: see text]. At 30% CO[Formula: see text], genes encoding CO[Formula: see text] uptake mechanisms, photosynthet

SUBMITTER: Geissler AS 

PROVIDER: S-EPMC12789804 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature