Life-course socio-economic factors associated with frailty in later life.

ABSTRACT:

Purpose

Frailty increases with age and is associated with negative health outcomes as falls, hospitalization, and mortality. Socio-economic situation (SES) in childhood and adulthood are associated with frailty. It is unclear how the interaction of childhood hardship and adulthood SES effects frailty.

Methods

A register-based study using data from national registers and from the Lolland-Falster Health Study, involving individuals aged 50 and above. Frailty status was assessed using a modified version of Fried's phenotype. Logistic regression models with multiple adjustments were used to analyze the odds of frailty. Causal interactions between economic hardship in adulthood, perception of childhood, self-reported stressful events in childhood, and self-reported educational le

SUBMITTER: Christensen MG 

PROVIDER: S-EPMC12790040 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature