Cardiac Troponin Screening and Clinical Outcomes in Patients Receiving Immunotherapy.

ABSTRACT:

Background

Immune checkpoint inhibitors (ICIs) are associated with cardiotoxicities such as myocarditis. However, data on the implementation and outcomes of cardiac biomarker screening remain limited.

Objectives

The aim of this study was to examine the impact of cardiac troponin I (cTnI) surveillance integrated with symptom-based triaging in patients receiving immunotherapy.

Methods

A single-center retrospective cohort study was conducted among adults who underwent routine serial cTnI monitoring during immunotherapy between January 2019 and October 2021. For patients with elevated cTnI, clinical presentation, management, and outcomes were analyzed. Major adverse cardiac events included arrhythmia, myocarditis, heart failure, acute coronary syndrome, stroke, and perica

SUBMITTER: Cheng E 

PROVIDER: S-EPMC12790047 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature