Predicting the Surge in Valve-in-Valve Volume: A Comparative Study of Japan and the United States.

ABSTRACT:

Background

Understanding trends in transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) utilization is essential for predicting valve-in-valve (ViV) TAVR usage, a viable option for failed bioprosthetic valves that presents a promising avenue for lifetime management of aortic stenosis.

Objectives

This study aimed to predict and compare the future annual ViV volume in the United States and Japan based on past and current TAVR/SAVR utilization under some underlying assumptions.

Methods

We developed a MATLAB-based Monte Carlo model engine to simulate the lifespan of bioprosthetic TAVR and SAVR valves. The valves are simulated for each individual TAVR/SAVR procedure from 1998 to 2035, accounting for over 4.4 million AVRs in the United

SUBMITTER: Ohno Y 

PROVIDER: S-EPMC12790052 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature