A feasibility study of a co-designed intervention to manage benzodiazepine dependence and high-risk use in those receiving opioid agonist treatment.

ABSTRACT:

Background

Problematic benzodiazepine use alongside opioids contributes to drug-related deaths among people who use drugs. Clinical management varies considerably. An intervention to address the root causes of benzodiazepine use with opioids has been developed, which included maintenance prescribing of diazepam with anxiety, sleep, and pain management, harm reduction, and safety conversations. This study tested the feasibility of recruiting and retaining people in the intervention to address 'street' benzodiazepine use. Outcome measures and economic evaluation data collection were piloted to determine the feasibility of a future trial.

Methods

The study tested the intervention in three sites (Grampian, Lothian and Fife) with a target of 15 patients per site. Inclusion criter

SUBMITTER: Matheson C 

PROVIDER: S-EPMC12790114 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature