Template-Controlled Mechanochemical Dissociation of a Rotaxane.

ABSTRACT: The mechanochemical dissociation of rotaxanes has been used in the design of materials with the ability to dissipate energy and of force-controlled release systems. The former takes advantage of the dissociation by dethreading, a noncovalent process in which the macrocycle is forced over a stopper, while in the latter, the forceful contact between the macrocycle and stopper provokes the rupture of a covalent bond and release of the stoppering unit. As the dissociation pathway is dictated by the relative size of the macrocycle and the stopper, a rotaxane under tension can usually only undergo one of these two pathways. However, the ability to control the mechanochemical reactivity of a rotaxane in situ would allow the creation of multiresponsive materials. Here, we show how to selectively a

SUBMITTER: Ormson J 

PROVIDER: S-EPMC12790351 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature