Non-targeted metabolomic profiling of <i>Cremastra appendiculata</i> providing insights for phytochemical analyses.

ABSTRACT:

Background

Cremastra appendiculata (D. Don) Makino, known as "Shan Cigu" in China, is a valuable medicinal plant historically employed for its antibacterial and anti-inflammatory properties. However, its comprehensive metabolome remains underexplored, hindering the establishment of standardized quality control.

Methods

In this study, a non-targeted metabolomics approach based on the Thermo Fisher Orbitrap Exploris 120 LC-MS (Liquid Chromatography-Mass Spectrometry) platform was employed to systematically profile the metabolites of C. appendiculata.

Results

A total of 174 compounds were annotated through a dual-validation workflow integrating Compound Discoverer 3.3 and manual tandem mass spectrometry spectral verification. Orthogonal partial least square

SUBMITTER: Guan R 

PROVIDER: S-EPMC12790786 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature