Fungal-specific IgG responses in allergic conjunctivitis: comparison with IgE and immunological implications.

ABSTRACT:

Background

Immunoglobulin G (IgG) is the most abundant antibody class in the bloodstream and is characterized by a long half-life compared to other immunoglobulins. While IgG plays a key role in host defense against infections, it is also known to be elevated in chronic inflammatory conditions. This study aimed to evaluate serum levels of fungus-specific Immunoglobulin E (IgE) and IgG antibodies in patients with allergic conjunctivitis and to investigate their associations with disease severity and sensitization status.

Methods

A total of 40 patients with allergic conjunctivitis and 20 healthy controls were enrolled. Serum levels of specific IgE and IgG antibodies against four common fungi-Alternaria, Aspergillus, Cladosporium, and Penicillium-wer

SUBMITTER: Mimura T 

PROVIDER: S-EPMC12790789 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature