Causal relationship between consumption of different tea types and the risk of stroke: A two-sample Mendelian randomization analysis.

ABSTRACT: This study aims to investigate whether the genetically predicted tea consumption of different types is causally associated with the risk of stroke. Four statistical datasets from genome-wide association studies (GWASs) related to tea consumption were employed. Seven distinct stroke types sourced from the European Bioinformatics Institute database were designated as outcomes. Two-sample univariate and multivariate Mendelian randomization (MVMR) analyses respectively were conducted to assess the causal relationship between tea consumption of different types and stroke risk. Two-sample MR analyses were conducted using 1061 single nucleotide polymorphisms as instrumental variables across seven stroke types. Univariate analyses showed that Rooibos tea intake was associated with large artery ath

SUBMITTER: Jiang X 

PROVIDER: S-EPMC12795082 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature