Intravenous tranexamic acid shows limited efficacy in arthroscopic shoulder surgery: a systematic review and meta-analysis of randomized-controlled trials.

ABSTRACT:

Purpose

The use of intravenous (IV) tranexamic acid (TXA) in arthroscopic shoulder surgery remains controversial. This meta-analysis aimed to evaluate the efficacy of IV TXA in improving perioperative outcomes during shoulder arthroscopy.

Methods

The review process was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A comprehensive systematic search was conducted in PubMed, Embase, Cochrane Library, and Web of Science from inception to February 2025. Randomized-controlled trials (RCTs) comparing IV TXA with group without TXA in patients undergoing arthroscopic shoulder surgery were included. Data were synthesized using random-effects models, with results presented as weighted mean differences (WMDs) and stand

SUBMITTER: Luo H 

PROVIDER: S-EPMC12796786 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature