Prognosis of liver transplantation and hepatectomy in patients with hepatocellular carcinoma meeting the Milan criteria: A systematic review and meta-analysis.

ABSTRACT: Liver transplantation (LT) and liver resection (LR) are two curative treatment options for patients with hepatocellular carcinoma (HCC) meeting the Milan criteria. However, the optimal choice between LT and LR remains contentious. The present meta-analysis aimed to provide additional evidence to optimize treatment decisions for patients with HCC. A comprehensive literature search was conducted across multiple databases, including PubMed, Embase, Cochrane, Web of Science (Medline), OVID, Scopus, China National Knowledge Infrastructure, Value-Added Information Provider, Wanfang and China Biology Medicine, focusing on studies reporting on the prognosis of LR and LT in patients with HCC. The data were analyzed using Review Manager 5.4 software. Random-effects models were employed to compare th

SUBMITTER: Wang J 

PROVIDER: S-EPMC12796872 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature