Identification of Polysialic Acid and Chondroitin-like Polysaccharides of <i>Moraxella bovis</i> Strains Associated with Infectious Bovine Keratoconjunctivitis.

ABSTRACT: Moraxella bovis is a major etiologic agent for infectious bovine keratoconjunctivitis (IBK), commonly known as bovine pink eye. IBK has been a major economic burden to the cattle and dairy industries due to its economic and welfare impacts on affected cattle herds. Antimicrobial treatment of acute IBK infections is often challenging. Vaccine formulations widely used in industry have poor efficacy for the prevention of IBK. Capsular polysaccharides of some bacterial pathogens are important epidemiological markers and are successfully used in vaccines for humans. Currently, there are limited data demonstrating the presence of capsular polysaccharides in M. bovis. In this study, we show by genomic analysis that a broad selection of M. bovis strains obtained from the eyes

SUBMITTER: Vionnet J 

PROVIDER: S-EPMC12797221 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature