Heterogeneous impacts of carbohydrate subtypes on the progression of microvascular complications in hyperglycemic individuals: evidence from the UK biobank.

ABSTRACT:

Background

Hyperglycemic individuals, who are prone to microvascular complications of diabetes (MCDs) like diabetic patients, may benefit from timely carbohydrate intake intervention. But there remain inconsistent results and lack of focus on carbohydrate subtypes, which may have distinct effects. This study aimed to investigate the associations between dietary carbohydrate subtypes and the MCDs incidence in hyperglycemic individuals.

Methods

Participants with hyperglycemia (defined as having either fasting plasma glucose ≥ 5.56 mmol/L or diabetes mellitus) were included from the UK Biobank cohort. Multivariable-adjusted Cox proportional hazards models and multi-state modelling were employed to estimate the associations of total carbohydrate, free sugars, starch, and fiber i

SUBMITTER: Wang J 

PROVIDER: S-EPMC12797509 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature