Impact of combined vector control interventions on Anopheles gambiae sensu lato resistance dynamics in a high pyrethroid resistance settings in Southwestern Burkina Faso.

ABSTRACT:

Background

The widespread emergence of insecticide resistance in malaria vectors, particularly Anopheles gambiae, poses a significant challenge to malaria control in sub-Saharan Africa. In Burkina Faso, where pyrethroid resistance is driven by both target-site mutations and enhanced metabolic detoxification, the efficacy of key vector control tools such as insecticide-treated nets (ITNs) and indoor residual spraying (IRS) has declined. In response, alternative non-pyrethroid interventions are being implemented. This study investigated the impact of non-pyrethroid IRS and piperonyl butoxide (PBO)-synergist pyrethroid ITNs on insecticide resistance dynamics in An. gambiae populations in Kampti and Gaoua, southwestern Burkina Faso.

Methods

Anopheles gambiae larvae were collecte

SUBMITTER: Ngaffo KL 

PROVIDER: S-EPMC12797545 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature