Ontology highlight
ABSTRACT: Background
Stage B heart failure (HF) requires precise risk stratification. Current guideline-recommended approaches focus on cardiac indicators, neglecting functional status. The Short Physical Performance Battery (SPPB) predicts outcomes in symptomatic HF, but its prognostic value for mortality in older adults with Stage B HF remains unexplored. This study aimed to evaluate this association, establish an optimal SPPB threshold, and determine the incremental value of SPPB and its subtests over conventional metrics.Methods
This prospective cohort enrolled patients with Stage B HF aged ≥ 65 years and followed them for 5 years to evaluate all-cause mortality. Restricted cubic splines were applied to explore potential non-linear relationships between SPPB and mortality. Progno
SUBMITTER: Ji C
PROVIDER: S-EPMC12797680 | biostudies-literature | 2025 Dec
REPOSITORIES: biostudies-literature