Evaluating the MedMira Multiplo® Complete Syphilis (TP/nTP) antibody test in a sexually transmitted infection clinic in Ottawa, Canada: increased rapid diagnosis and improved antibiotic stewardship.

ABSTRACT:

Background

Syphilis now affects every population and serology is the mainstay of diagnosis. The issue is that serology has a turnaround time of several days. One solution is point-of-care tests (POCTs), which can provide results in minutes. We consequently evaluated the MedMira Multiplo® Complete Syphilis Test in an STI clinic in Ottawa, Canada.

Methods

Anyone 16 + years old who consented and was undergoing syphilis testing at our clinic was eligible. Those who enrolled completed the POCT and saw a clinician to review their result. We calculated sensitivities and specificities for the POCT, compared to serology and diagnosis.

Results

From August 2024 to May 2025, we performed 622 syphilis POCTs on 600 participants. Compared to serology when chemiluminescent microparti

SUBMITTER: O'Byrne P 

PROVIDER: S-EPMC12797785 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature