Sarcopenia index is a superior prognostic marker to creatinine-cystatin C ratio in older adults with hip fracture.

ABSTRACT:

Background

Sarcopenia is prevalent in older adults with hip fracture and is associated with poor postoperative outcomes. This study aimed to evaluate the prognostic value of sarcopenia index (SI) and creatinine-cystatin C ratio (CCR) in predicting postoperative mortality in older patients with hip fracture.

Methods

A retrospective study was conducted on 485 older adults (aged ≥ 65 years) with hip fracture treated at Zhongda Hospital between January 2018 and December 2022. SI and CCR were calculated using serum creatinine and cystatin C. The primary outcome was all-cause mortality at 1, 3, and 12 months.

Results

Among the 485 patients, 46 (9.5%) died within one year. Both SI and CCR presented positive and significant correlations with muscle mass and density, while SI

SUBMITTER: Sheng R 

PROVIDER: S-EPMC12797931 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature