Mental health and body mass index in early pregnancy: a secondary analysis of three randomised controlled trials.

ABSTRACT:

Objective

Overweight and obesity in pregnant women have been associated with an increased risk of depression and anxiety, but the strength of these associations and the influence of confounders remain uncertain. Understanding these associations may help identify women at risk in early pregnancy and guide targeted support. This study aimed to quantify associations between maternal body mass index (BMI) and symptoms of depression, anxiety, and health-related quality of life (HRQoL) in early pregnancy and to assess whether they persisted after adjustment for confounders.

Methods

This secondary analysis pooled baseline data from three randomised controlled trials including women at gestational week 10 + 0 to 20 + 0: LIMIT (BMI ≥ 25.0 kg/m²), GRoW (BMI ≥ 25.0 kg/m²) and OPTIMISE

SUBMITTER: Kornerup N 

PROVIDER: S-EPMC12798114 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature