Connectivity and function are coupled across cognitive domains throughout the brain.

ABSTRACT: Decades of neuroimaging have revealed that the functional organization of the brain is roughly consistent across individuals, and at rest, it resembles group-level task-evoked networks. A fundamental assumption in the field is that the functional specialization of a brain region arises from its connections to the rest of the brain, but limitations in the amount of data that can be feasibly collected in a single individual leave open the following question: Is the association between task activation and connectivity consistent across the brain and many cognitive tasks? To answer this question, we fit ridge regression models to activation maps from 33 cognitive domains (generated with NeuroQuery) using resting-state functional connectivity data from the Human Connectome Project as the predic

SUBMITTER: Hiersche KJ 

PROVIDER: S-EPMC12798649 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature