The impact of heart rate on echocardiographic measures of left ventricular function: novel insights facilitated by deep learning.

ABSTRACT:

Background

Echocardiographic measurements of the left ventricle (LV) are fundamental in diagnosing and monitoring cardiac disease. Still, current understanding of how heart rate influences these measurements is incomplete. We aimed to explore the relationship between heart rate and LV global longitudinal strain (GLS), ejection fraction (LVEF), end-diastolic (LVEDV), and end-systolic volumes (LVESV), using atrial pacing and a transparent multi-step deep learning (DL)-based method for fully automated measurements.

Methods and results

Fifty participants with permanent pacemakers were enrolled. Heart rate was increased by atrial pacing in increments of 10 beats/min, from 50 to 140 beats/min, with echocardiographic 10-beat cine-loops recorded at each step. A DL-based method was u

SUBMITTER: Woelfert A 

PROVIDER: S-EPMC12798807 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature