Probiotics in Term Infants: Clinical Impact of Infant-Type Bifidobacteria: A Systematic Review and Meta-analyses.

ABSTRACT: Probiotics labeled "infant-type bifidobacteria" (ITB), such as the B. longum subsp. infantis strains, have gained significant attention in recent years for their potential to positively influence the gut microbiome, early immune system development, and consequently future health. However, significant knowledge gaps remain regarding the actual clinical impact, the optimal strains, dosing regimens, and treatment duration-both in general and for ITB-probiotics specifically. This systematic review evaluates the clinical effects of administering ITB-probiotics to healthy, term infants within the first year of life. The aim was to address all categories of clinical outcomes. However, the included studies focused primarily on antibiotic use, atopic conditions, gastrointestinal health, and growth.

SUBMITTER: Sjælland MA 

PROVIDER: S-EPMC12799449 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature