The prognostic value of circulating soluble ST2 in patients with chronic heart failure.

ABSTRACT: ObjectiveThe purpose of this study was to assess whether circulating soluble ST2 independently predicts prognosis in patients with chronic heart failure.MethodsThis study was registered with the International Prospective Register of Systematic Reviews (PROSPERO) under the unique registration number CRD42023489018. Two researchers systematically searched PubMed, Embase, and Web of Science for all studies published up to 1 September 2024. To evaluate the quality of the study, the Newcastle-Ottawa Scale was used; Review Manager software was used for statistical analysis and construction of forest plots.ResultsThe final analysis comprised 17 studies in total. This meta-analysis demonstrated that a high soluble ST2 level was a predictor of poor all-cause mortality (hazard ratio: 1.03, 95% confi

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC12799978 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature